Statin-Antibiotic Combo Fails in Decompensated Cirrhosis

Adding combination treatment with simvastatin and rifaximin to standard therapy did not prevent severe complications in patients with decompensated cirrhosis, a European randomized trial found. Published in JAMA, the double-blind, placebo-controlled, phase 3 LIVERHOPE trial was conducted in 14 European hospitals from January 2019 to December 2022…